Descriptors Found: 1
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Descriptor English:   Proto-Oncogene Proteins c-met 
Descriptor Spanish:   Proteínas Proto-Oncogénicas c-met 
Descriptor Portuguese:   Proteínas Proto-Oncogênicas c-met 
Synonyms English:   HGF Receptor
Hepatocyte Growth Factor Receptor
MET Proto Oncogene, Receptor Tyrosine Kinase
MET Proto-Oncogene, Receptor Tyrosine Kinase
MET Receptor Tyrosine Kinase
Proto Oncogene Proteins c met
Proto-Oncogene Proteins, met
Receptor, HGF
Receptor, Hepatocyte Growth Factor
Receptor, Scatter Factor
Scatter Factor Receptor
c Met Receptor Tyrosine Kinase
c met Proteins
c-Met Receptor Tyrosine Kinase
c-met Proteins
met Proto Oncogene Proteins
met Proto-Oncogene Proteins  
Tree Number:   D08.811.913.696.620.682.725.400.075
Definition English:   Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia. 
History Note English:   2006, 1998-1999 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   33476 
Unique Identifier:   D019859 

Occurrence in VHL: