Descriptors Found: 1
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Descriptor English:   Platelet Factor 3 
Descriptor Spanish:   Factor Plaquetario 3 
Descriptor Portuguese:   Fator Plaquetário 3 
Synonyms English:   Factor 3, Platelet
PF 3  
Tree Number:   D12.776.124.125.691
Definition English:   A phospholipid from the platelet membrane that contributes to the blood clotting cascade by forming a phospholipid-protein complex (THROMBOPLASTIN) which serves as a cofactor with FACTOR VIIA to activate FACTOR X in the extrinsic pathway of BLOOD COAGULATION. 
Indexing Annotation English:   a coagulant
Pharmacological Action:   Coagulants
History Note English:   91(75); was see under BLOOD COAGULATION FACTORS 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   22258 
Unique Identifier:   D010977 

Occurrence in VHL: