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Descriptor English:   Luteinizing Hormone 
Descriptor Spanish:   Hormona Luteinizante 
Descriptor Portuguese:   Hormônio Luteinizante 
Synonyms English:   Hormone, Interstitial Cell-Stimulating
Hormone, Luteinizing
ICSH (Interstitial Cell Stimulating Hormone)
Interstitial Cell Stimulating Hormone
Interstitial Cell-Stimulating Hormone
LH (Luteinizing Hormone)
Tree Number:   D06.472.699.322.576.463
Definition English:   A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity. 
Indexing Annotation English:   do not confuse X ref LUTROPIN with PLACENTAL LUTEOTROPIN; for alpha subunit, coordinate with GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; LUTEINIZING HORMONE, BETA SUBUNIT is also available
See Related English:   Receptors, LH
History Note English:   2003 (1968); use ICSH 1963-1967 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   22739 
Unique Identifier:   D007986 

Occurrence in VHL: