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ALPHA-AMANITIN
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DeCS
Descriptor
English
:
Alpha-Amanitin
Descriptor
Spanish
:
Alfa-Amanitina
Descriptor
Portuguese
:
Alfa-Amanitina
Synonyms
English
:
Alpha Amanitin
Alpha Amanitine
Alpha-Amanitine
Tree Number:
D04.345.566.050.111
D12.644.456.050.111
D12.644.641.050.111
D23.946.587.175.111
Definition
English
:
A cyclic octapeptide with a thioether bridge between the
cystine
and
tryptophan
. It inhibits
RNA POLYMERASE II
.
Poisoning
may require
LIVER TRANSPLANTATION.
Pharmacological Action:
Poisons
Nucleic Acid Synthesis Inhibitors
See Related
English
:
Mushroom Poisoning
History Note
English
:
2008; use AMANITINS 1980-2007
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
52652
Unique Identifier:
D053959
Occurrence in VHL
:
Similar:
DeCS