1 / 1
|
DeCS
|
|
|
Descriptor English:
|
|
Hypoglycins
|
Descriptor Spanish:
|
|
Hipoglicinas
|
Descriptor Portuguese:
|
|
Hipoglicinas
|
Tree Number:
|
|
D02.455.426.392.368.533.450
D23.946.412
|
Definition English:
|
|
Methylene cyclopropyl alanine and congeners isolated from the unripe edible fruit of the AKEE plant (BLIGHIA SAPIDA). Hypoglycin B is the gamma-glutamyl congener of hypoglycin A. They are very toxic and teratogenic, causing a syndrome called Jamaican vomiting sickness that includes a fall in blood glucose due to the interference of FATTY ACIDS and LEUCINE metabolism which leads to VOMITING, liver damage, CONVULSIONS and DEATH. |
Indexing Annotation English:
|
|
Jamaican vomiting sickness : coordinate HYPOGLYCINS /pois (IM) with PLANT POISONING (IM)
|
Pharmacological Action:
|
|
Poisons
|
History Note English:
|
|
91(77); was see under CYCLOPROPANES 1977-90
|
Allowable Qualifiers English:
|
|
|
Record Number:
|
|
7183
|
Unique Identifier:
|
|
D007005
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS
|