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GLYCOPROTEIN IA IIA
Descriptors Found:
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DeCS
Descriptor
English
:
Integrin alpha2beta1
Descriptor
Spanish
:
Integrina alfa2beta1
Descriptor
Portuguese
:
Integrina alfa2beta1
Synonyms
English
:
CD49b CD29
CD49b-CD29
Glycoprotein Ia IIa
Glycoprotein Ia-IIa
Late Antigen-2, Very
Platelet Membrane Glycoprotein Heterodimer Ia IIa
Platelet Membrane Glycoprotein Heterodimer Ia-IIa
VLA 2
VLA-2
Very Late Antigen 2
Very Late Antigen-2
alpha2beta1, Integrin
alpha2beta1Integrin
Tree Number:
D12.776.395.550.625.298
D12.776.543.550.625.298
D12.776.543.750.685.200
D12.776.543.750.705.408.530.249
D12.776.543.750.705.408.850.199
D12.776.543.750.705.675.352
D12.776.543.750.705.876.280
Definition
English
:
An integrin found on
fibroblasts
, platelets, endothelial and
epithelial cells
, and
lymphocytes
where it functions as a receptor for
COLLAGEN
and
LAMININ
. Although originally referred to as the
collagen
receptor, it is one of several receptors for
collagen
. Ligand binding to
integrin alpha2beta1
triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.
History Note
English
:
2003; for VLA-2 use COLLAGEN RECEPTORS (NM) 1991-2002; for PLATELET MEMBRANE GLYCOPROTEIN HETERODIMER IA-IIA use COLLAGEN RECEPTORS (NM) 1992-2000; for INTEGRIN ALPHA2BETA1 & CD49B-CD29 use COLLAGEN RECEPTORS (NM) 1994-2002; for ALPHA2BETA1INTEGRIN use COLLAGEN RECEPTORS (NM) 2001-2002
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
37449
Unique Identifier:
D038982
Occurrence in VHL
:
Similar:
DeCS