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DeCS
Descriptor
English
:
Ancrod
Descriptor
Spanish
:
Ancrod
Descriptor
Portuguese
:
Ancrod
Synonyms
English
:
Agkistrodon Serine Proteinase
Agkistrodon rhodostoma Venom Protease
Arvin
Arvin IRC 50
Arvin IRC-50
Arvin IRC50
Arwin
Venacil
Tree Number:
D08.811.277.656.300.760.955.060
D08.811.277.656.959.350.955.060
D20.888.850.960.200.050
D23.946.833.850.960.200.050
Definition
English
:
An enzyme fraction from the venom of the Malayan pit viper,
Agkistrodon
rhodostoma. It catalyzes the
hydrolysis
of a number of amino acid
esters
and a limited
proteolysis
of
fibrinogen
. It is used clinically to produce controlled defibrination in
patients
requiring anticoagulant therapy. EC 3.4.21.-.
Pharmacological Action:
Anticoagulants
Fibrinolytic Agents
History Note
English
:
78; was ARVIN see under ENDOPEPTIDASES 1975-77; ARVIN was see ANCROD 1978-95
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23155
Unique Identifier:
D000721
Occurrence in VHL
:
Similar:
DeCS