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DeCS
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Descriptor English:
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Antigenic Modulation
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Descriptor Spanish:
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Modulación Antigénica
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Descriptor Portuguese:
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Modulação Antigênica
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Synonyms English:
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Antigenic Modulations
Modulation, Antigenic
Modulations, Antigenic
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Tree Number:
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G12.122.140
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Definition English:
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Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies. |
History Note English:
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92
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Allowable Qualifiers English:
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Record Number:
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30261
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Unique Identifier:
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D016525
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Occurrence in VHL:
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Similar:
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DeCS
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